Study of a Male Contraceptive
Method Under Development

Are you considering a vasectomy?

Are you between 25 and 65 years old and in good health?

Would you like to help develop a new contraceptive method for men?

This study may be of interest to you.

During a vasectomy, the vas deferens, the tube that carries sperm toward the prostate during
ejaculation, is divided and blocked. This research study aims to evaluate the safety and
effectiveness of a hydrogel injected into the vas deferens to block the passage of sperm. The vas
deferens is accessed through the scrotum to insert the hydrogel, using an approach similar to a
no-scalpel vasectomy.

A video on the NEXT Life Sciences website demonstrates how it works: https://www.planaformen.com/science

After the hydrogel is placed, participants will be followed for six months. Following this period, they will have three options:

01

Have the hydrogel removed and undergo a vasectomy immediately.

02

Keep the hydrogel plug in place and participate in longer-term follow-up.

03

Have the hydrogel removed to assess the return of sperm to the ejaculate,
followed by a vasectomy three months later.

The study requires blood tests, semen analyses, and follow-up appointments by telephone or in person. Financial compensation will be provided for the time and participation involved in the study.

If you are interested in learning more or participating in this study.

OR

We will contact you to provide further information.